Publications

2015

Mechanisms of disease: The human N-glycome. Biochim Biophys Acta. 2015 Oct 20. pii: S0304-4165(15)00288-3. doi: 10.1016/j.bbagen.2015.10.016. [Epub ahead of print] PubMed PMID: 26500099.

PubMed link
Lauc G, Pezer M, Rudan I, Campbell H.
2015

Systemic lupus erythematosus associates with the decreased immunosuppressive potential of the IgG glycome. Arthritis Rheumatol. 2015 Jul 21. doi: 10.1002/art.39273. [Epub ahead of print] PubMed PMID: 26200652.

PubMed link
Vučković F, Krištić J, Gudelj I, Teruel Artacho M, Keser T, Pezer M, Pučić-Baković M, Štambuk J, Trbojević-Akmačić I, Barrios C, Pavić T, Menni C, Wang Y, Zhou Y, Cui L, Song H, Zeng Q, Guo X, Pons-Estel BA, McKeigue P, Patrick AL, Gornik O, Spector TD, Harjaček M, Alarcon-Riquelme M, Molokhia M, Wang W, Lauc G.
2015

Glycosylation Profile of IgG in Moderate Kidney Dysfunction. J Am Soc Nephrol. J Am Soc Nephrol. 2015 Jul 16. pii: ASN.2015010109. [Epub ahead of print] PubMed PMID: 26185202.

PubMed link
Barrios C, Zierer J, Gudelj I, Štambuk J, Ugrina I, Rodríguez E, Soler MJ, Pavić T, Šimurina M, Keser T, Pučić-Baković M, Mangino M, Pascual J, Spector TD, Lauc G, Menni C.
2015

IBD-BIOM Consortium. Inflammatory bowel disease associates with proinflammatory potential of the immunoglobulin G glycome. Inflamm Bowel Dis. 2015 Jun;21(6):1237-47. doi: 10.1097/MIB.0000000000000372. PubMed PMID: 25895110; PubMed Central PMCID:PMC4450892.

PubMed link
Trbojević Akmačić I, Ventham NT, Theodoratou E, Vučković F, Kennedy NA, Krištić J, Nimmo ER, Kalla R, Drummond H, Štambuk J, Dunlop MG, Novokmet M,Aulchenko Y, Gornik O, Campbell H, Pučić Baković M, Satsangi J, Lauc G.
2015

Estimation of human age using N-glycan profiles from bloodstains. Int J Legal Med. 2015 Sep;129(5):955-61. doi:10.1007/s00414-015-1162-x. Epub 2015 Mar 19. PubMed PMID: 25787342; PubMed Central PMCID: PMC4550657.

PubMed link
Gudelj I, Keser T, Vučković F, Škaro V, Goreta SŠ, Pavić T, Dumić J, Primorac D, Lauc G, Gornik O.
2014

The role of glycosylation in IBD. Nat Rev Gastroenterol Hepatol. 2014 Oct;11(10):588-600. doi: 10.1038/nrgastro.2014.78. Epub 2014 Jun 10. Review. PubMed PMID: 24912389.

PubMed link
Theodoratou E, Campbell H, Ventham NT, Kolarich D, Pučić-Baković M, Zoldoš V, Fernandes D, Pemberton IK, Rudan I, Kennedy NA, Wuhrer M, Nimmo E, Annese V, McGovern DP, Satsangi J, Lauc G.
2014

Comparative performance of four methods for high-throughput glycosylation analysis of immunoglobulin G in genetic and epidemiological research. Mol Cell Proteomics. 2014 Jun;13(6):1598-610. doi: 10.1074/mcp.M113.037465. Epub 2014 Apr 9. PubMed PMID: 24719452; PubMed Central PMCID: PMC4047478.

PubMed link
Huffman JE, Pučić-Baković M, Klarić L, Hennig R, Selman MH, Vučković F, Novokmet M, Krištić J, Borowiak M, Muth T, Polašek O, Razdorov G, Gornik O, Plomp R, Theodoratou E, Wright AF, Rudan I, Hayward C, Campbell H, Deelder AM, Reichl U, Aulchenko YS, Rapp E, Wuhrer M, Lauc G.
2014

Changes in IgG and total plasma protein glycomes in acute systemic inflammation. Sci Rep. 2014 Mar 11;4:4347. doi: 10.1038/srep04347. PubMed PMID: 24614541; PubMed Central PMCID: PMC3949295.

PubMed link
Novokmet M, Lukić E, Vučković F, Ðurić Ž, Keser T, Rajšl K, Remondini D, Castellani G, Gašparović H, Gornik O, Lauc G.
2014

Glycans – the third revolution in evolution. Front Genet. 2014 May 23;5:145. doi: 10.3389/fgene.2014.00145. eCollection 2014. PubMed PMID: 24904645; PubMed Central PMCID: PMC4033155.

PubMed link
Lauc G, Krištić J, Zoldoš V.
2014

Glycans are a novel biomarker of chronological and biological ages. J Gerontol A Biol Sci Med Sci. 2014 Jul;69(7):779-89. doi: 10.1093/gerona/glt190. Epub 2013 Dec 10. PubMed PMID: 24325898; PubMed Central PMCID: PMC4049143.

PubMed link
Krištić J, Vučković F, Menni C, Klarić L, Keser T, Beceheli I, Pučić-Baković M, Novokmet M, Mangino M, Thaqi K, Rudan P, Novokmet N, Sarac J, Missoni S, Kolčić I, Polašek O, Rudan I, Campbell H, Hayward C, Aulchenko Y, Valdes A, Wilson JF, Gornik O, Primorac D, Zoldoš V, Spector T, Lauc G.
2013

Glycosylation of immunoglobulin g: role of genetic and epigenetic influences. PLoS One. 2013 Dec 6;8(12):e82558. doi: 10.1371/journal.pone.0082558. eCollection 2013. PubMed PMID: 24324808; PubMed Central PMCID: PMC3855797.

PubMed link
Menni C, Keser T, Mangino M, Bell JT, Erte I, Akmačić I, Vučković F, Pučić Baković M, Gornik O, McCarthy MI, Zoldoš V, Spector TD, Lauc G, Valdes AM.
2013

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. PLoS Genet. 2013;9(1):e1003225. doi: 10.1371/journal.pgen.1003225. Epub 2013 Jan 31. PubMed PMID: 23382691; PubMed Central PMCID: PMC3561084.

PubMed link
Lauc G, Huffman JE, Pučić M, Zgaga L, Adamczyk B, Mužinić A, Novokmet M, Polašek O, Gornik O, Krištić J, Keser T, Vitart V, Scheijen B, Uh HW, Molokhia M, Patrick AL, McKeigue P, Kolčić I, Lukić IK, Swann O, van Leeuwen FN, Ruhaak LR, Houwing-Duistermaat JJ, Slagboom PE, Beekman M, de Craen AJ, Deelder AM, Zeng Q, Wang W, Hastie ND, Gyllensten U, Wilson JF, Wuhrer M, Wright AF, Rudd PM, Hayward C, Aulchenko Y, Campbell H, Rudan I.
2013

High-throughput IgG Fc N-glycosylation profiling by mass spectrometry of glycopeptides. J Proteome Res. 2013 Feb 1;12(2):821-31. doi: 10.1021/pr300887z. Epub 2013 Jan 18. PubMed PMID: 23298168.

PubMed link
Baković MP, Selman MH, Hoffmann M, Rudan I, Campbell H, Deelder AM, Lauc G, Wuhrer M.
2013

Mutations in HNF1A result in marked alterations of plasma glycan profile. Diabetes. 2013 Apr;62(4):1329-37. doi: 10.2337/db12-0880. Epub 2012 Dec 28. PubMed PMID: 23274891; PubMed Central PMCID: PMC3609552.

PubMed link
Thanabalasingham G, Huffman JE, Kattla JJ, Novokmet M, Rudan I, Gloyn AL, Hayward C, Adamczyk B, Reynolds RM, Muzinic A, Hassanali N, Pucic M, Bennett AJ, Essafi A, Polasek O, Mughal SA, Redzic I, Primorac D, Zgaga L, Kolcic I, Hansen T, Gasperikova D, Tjora E, Strachan MW, Nielsen T, Stanik J, Klimes I, Pedersen OB, Njølstad PR, Wild SH, Gyllensten U, Gornik O, Wilson JF, Hastie ND, Campbell H, McCarthy MI, Rudd PM, Owen KR, Lauc G, Wright AF.
2013

The association between galactosylation of immunoglobulin G and body mass index. Prog Neuropsychopharmacol Biol Psychiatry. 2014 Jan 3;48:20-5. doi: 10.1016/j.pnpbp.2013.08.014. Epub 2013 Sep 5. PubMed PMID: 24012618.

PubMed link
Nikolac Perkovic M, Pucic Bakovic M, Kristic J, Novokmet M, Huffman JE, Vitart V, Hayward C, Rudan I, Wilson JF, Campbell H, Polasek O, Lauc G, Pivac N.
2013

Genomics and epigenomics of the human glycome. Glycoconj J. 2013 Jan;30(1):41-50. doi: 10.1007/s10719-012-9397-y. Epub 2012 May 31. Review. PubMed PMID: 22648057.

PubMed link
Zoldoš V, Novokmet M, Bečeheli I, Lauc G.
2012

Changes in plasma and IgG N-glycome during childhood and adolescence. Glycobiology. 2012 Jul;22(7):975-82. doi: 10.1093/glycob/cws062. Epub 2012 Mar 16. PubMed PMID: 22426998.

PubMed link
Pucic M, Muzinic A, Novokmet M, Skledar M, Pivac N, Lauc G, Gornik O.
2012

Genomics and epigenomics of the human glycome. Glycoconj J. 2013 Jan;30(1):41-50. doi: 10.1007/s10719-012-9397-y. Epub 2012 May 31. Review. PubMed PMID: 22648057.

PubMed link
Zoldoš V, Novokmet M, Bečeheli I, Lauc G.
2012

The future of glycoscience. Biochim Biophys Acta. 2012 Sep;1820(9):1305. doi: 10.1016/j.bbagen.2012.03.001. PubMed PMID: 22727214.

PubMed link
Lauc G.
2012

Epigenetic silencing of HNF1A associates with changes in the composition of the human plasma N-glycome. Epigenetics. 2012 Feb;7(2):164-72. doi: 10.4161/epi.7.2.18918. PubMed PMID: 22395466; PubMed Central PMCID: PMC3335910.

PubMed link
Zoldoš V, Horvat T, Novokmet M, Cuenin C, Mužinić A, Pučić M, Huffman JE,
Gornik O, Polašek O, Campbell H, Hayward C, Wright AF, Rudan I, Owen K, McCarthy
MI, Herceg Z, Lauc G.
2011

Evolutional and clinical implications of the epigenetic regulation of protein glycosylation. Clin Epigenetics. 2011 Aug;2(2):425-32. doi: 10.1007/s13148-011-0039-1. Epub 2011 Jun 14. PubMed PMID: 22704355; PubMed Central PMCID: PMC3365393.

PubMed link
Horvat T, Zoldoš V, Lauc G.